Komplikasi metabolik dan endokrin jangka panjang pada wanita setelah kehamilan dengan Diabetes Gestasional

Authors

  • Rika Wulandari Universitas Nurul Jadid
  • Yusri Dwi Lestari Universitas Nurul Jadid

DOI:

https://doi.org/10.62354/jurnalmedicare.v4i4.271

Keywords:

gestational diabetes, metabolic complications, post pregnancy screening

Abstract

Gestational diabetes (GDM) is a condition of increased blood glucose levels that is first detected during pregnancy, and not only affects the mother during pregnancy, but also increases the risk of long-term metabolic and endocrine complications after delivery. Women with a history of GDM are at higher risk of developing type 2 diabetes, dyslipidemia, thyroid disorders, and polycystic ovary syndrome (PCOS). These metabolic complications can appear within 5 to 20 years after pregnancy, with insulin resistance as the main triggering factor. In addition, thyroid disorders and PCOS can interfere with hormone function, which has an impact on the body's metabolic balance and reproductive health. Some risk factors that contribute to these long-term complications are obesity, family history of diabetes, age, and post-pregnancy lifestyle. Proper handling through routine screening, healthier lifestyle changes, and medical therapy are needed to reduce the risk of complications and improve the quality of life of women after pregnancy. With early detection and effective prevention, long-term complications due to GDM can be minimized, which can ultimately prevent women from the risk of other chronic diseases.

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References

Akhalya, K., Sreelatha, S., Rajeshwari, R., & Shruthi, K. (2019). A review article-gestational diabetes mellitus. Endocrinol Metab Int J, 7(1), 26–39. https://doi.org/10.15406/emij.2019.07.00238

Alfadhli, E. M. (2015). Gestational diabetes mellitus. Saudi Medical Journal, 36(4), 399–406. https://doi.org/10.15537/smj.2015.4.10307

Huopio, H., Hakkarainen, H., Pääkkönen, M., Kuulasmaa, T., Voutilainen, R., Heinonen, S., & Cederberg, H. (2014). Long-term changes in glucose metabolism after gestational diabetes: a double cohort study. BMC Pregnancy and Childbirth, 14(1), 296. https://doi.org/10.1186/1471-2393-14-296

Ikatan Dokter Indonesia. (2019). Buku Panduan Neonatal UKK Neonatologi PP IDAI. IDAI. https://www.idai.or.id/tentang-idai/struktur/badan-pelengkap/ukk/neonatologi

Kementerian Kesehatan Republik Indonesia. (2020). Pedoman Pelayanan Antenatal, Persalinan, Nifas, dan Bayi Baru Lahir di Era Adaptasi Kebiasaan Baru. Kementerian Kesehatan RI. https://repository.kemkes.go.id/book/624

Lilly, L. S. (2016). Pathophysiology of Heart Disease: A Collaborative Project of Medical Students and Faculty (6th (ed.)). Wolters Kluwer. https://books.google.com/books/about/Pathophysiology_of_Heart_Disease.html?id=6_a5oQEACAAJ

Liong, B. K. (2016). Patofisiologi, Skrining, dan Diagnosis Laboratorium Diabetes Melitus Gestasional. CDK Journal, 43(11), 811–813. https://www.neliti.com/publications/398823/patofisiologi-skrining-dan-diagnosis-laboratorium-diabetes-melitus-gestasional

Moore, L. E. (2018). Diabetes in Pregnancy: The Complete Guide to Management (1st (ed.)). Springer International Publishing. https://doi.org/10.1007/978-3-319-65518-5

Mpondo, B. C. T., Ernest, A., & Dee, H. E. (2015). Gestational diabetes mellitus: challenges in diagnosis and management. Journal of Diabetes & Metabolic Disorders, 14(1), 42. https://doi.org/10.1186/s40200-015-0169-7

Noctor, E., & Dunne, F. P. (2015). Type 2 diabetes after gestational diabetes: The influence of changing diagnostic criteria. World Journal of Diabetes, 6(2), 234–244. https://doi.org/10.4239/wjd.v6.i2.234

Parham, M., Asgarani, F., Bagherzadeh, M., Ebrahimi, G., & Vafaeimanesh, J. (2015). Thyroid function in pregnant women with gestational diabetes: Is screening necessary? Thyroid Research and Practice, 12(1), 3–7. https://doi.org/10.4103/0973-0354.147271

Plows, J. F., Stanley, J. L., Baker, P. N., Reynolds, C. M., & Vickers, M. H. (2018). The Pathophysiology of Gestational Diabetes Mellitus. International Journal of Molecular Sciences, 19(11), 3342. https://doi.org/10.3390/ijms19113342

Rahayu, A., & Rodiani. (2016). Efek Diabetes Melitus Gestasional terhadap Kelahiran Bayi Makrosomia. Majority, 5(4), 17–22. https://jurnal.unismuhpalu.ac.id/index.php/JKS/article/view/2906/2415

Reeder, C. F., Hambright, A. A., & Fortner, K. B. (2018). Dyspnea in Pregnancy: A Case Report of a Third Trimester Mediastinal Mass in Pregnancy. American Journal of Case Reports, 19, 1536–1540. https://doi.org/10.12659/AJCR.910725

Soewondo, P., & Pramono, L. A. (2011). Prevalence, characteristics, and predictors of pre-diabetes in Indonesia. Medical Journal of Indonesia, 20(4), 283–294. https://doi.org/10.13181/mji.v20i4.465

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Published

2025-10-31

How to Cite

Rika Wulandari, & Yusri Dwi Lestari. (2025). Komplikasi metabolik dan endokrin jangka panjang pada wanita setelah kehamilan dengan Diabetes Gestasional . Jurnal Medicare, 4(4), 874–883. https://doi.org/10.62354/jurnalmedicare.v4i4.271