PREVALENCE AND CLINICAL SPECIMEN DISTRIBUTION OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) AT JEMURSARI ISLAMIC HOSPITAL SURABAYA IN 2020

Authors

  • Marinda Dwi Puspitarini Department of Microbiology, Faculty of Medicine, Universitas Nahdlatul Ulama Surabaya
  • Diah Retno Kusumawati Department of Microbiology, Faculty of Medicine, Universitas Nahdlatul Ulama Surabaya
  • Yunyastiti Dwidya Palupi Faculty of Medicine Universitas Nahdlatul Ulama Surabaya
  • Yuriske Agnovianto Faculty of Medicine Universitas Nahdlatul Ulama Surabaya

DOI:

https://doi.org/10.62354/jurnalmedicare.v5i4.545

Abstract

Background: Methicillin-Resistant Staphylococcus aureus (MRSA) represents a critical pathogen responsible for healthcare-associated infections (HAIs), posing formidable therapeutic challenges due to acquired resistance against nearly all β-lactam antibiotics via PBP2a production. Routine microbiological surveillance in secondary and tertiary referral hospitals is imperative to formulate institutional antibiograms and guide rational empirical antimicrobial regimens.

Objective: To determine the prevalence of MRSA among clinical Staphylococcus aureus isolates and analyze its distribution across specimen types and patient age brackets at Jemursari Islamic Hospital Surabaya during 2020. Methods: A descriptive retrospective cross-sectional study was conducted utilizing secondary laboratory culture databases and medical records from the Clinical Pathology Laboratory of Jemursari Islamic Hospital Surabaya between January and December 2020. All confirmed Staphylococcus aureus isolates fulfilling inclusion criteria were analyzed. Variables evaluated encompassed methicillin-resistance phenotypes (MSSA vs. MRSA), clinical specimen origins, and patient age strata. Data were synthesized using frequency distributions and relative percentages.

Results: A total of 23 non-duplicate Staphylococcus aureus isolates were identified across the one-year surveillance window. Methicillin-Sensitive Staphylococcus aureus (MSSA) accounted for 17 isolates (73.9%), while Methicillin-Resistant Staphylococcus aureus (MRSA) comprised 6 isolates, establishing an overall institutional MRSA prevalence of 26.1%. Stratified by clinical specimen type, MRSA isolates were predominantly recovered from pus/wound exudates (66.7%, n = 4), followed by sputum specimens (33.3%, n = 2). Age-stratified analysis revealed that MRSA was most frequently recovered from older adult patients aged 51–60 years (33.3%, n = 2), with single isolates (16.7% each) identified in age groups 11–20, 21–30, 31–40, and 61–70 years.

Conclusion: The prevalence of MRSA at Jemursari Islamic Hospital Surabaya in 2020 was 26.1%, predominantly originating from purulent soft tissue and respiratory specimens in older adult inpatients. Continuous microbiological surveillance, implementation of strict antimicrobial stewardship programs (ASP), and rigorous infection prevention and control (IPC) protocols are vital to curb the transmission of resistant clones.

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Keywords:

Antimicrobial resistance, Hospital infection, Inpatient care, Methicillin-Resistant Staphylococcus aureus (MRSA), Pus specimen, Surveillance

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Published

2026-10-31

How to Cite

Dwi Puspitarini, M., Retno Kusumawati, D., Dwidya Palupi, Y., & Agnovianto, Y. (2026). PREVALENCE AND CLINICAL SPECIMEN DISTRIBUTION OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) AT JEMURSARI ISLAMIC HOSPITAL SURABAYA IN 2020. Jurnal Medicare, 5(4), 1878–1887. https://doi.org/10.62354/jurnalmedicare.v5i4.545

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Vol. 5 No. 4 (2026): OCTOBER 2026

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